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KMID : 0903519950380060577
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1995 Volume.38 No. 6 p.577 ~ p.580
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An Antibiotic against Multidrug - resistant Staphylococcus aureus Produced by Strain CNU30122
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김창진/Kim, Chang Jin
유익동/윤봉식/조수묵/Yoo, Ick Dong/Yun, Bong Sik/Cho, Soo Muk
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Abstract
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During the screening for the antimicrobial agents against multidrug-resistant Staphylococcus aureus, we isolated an active compound produced by strain CNU30122. The active compound was purified from culture broth by HP-20 column chromatography, ethylacetate extraction. silica gel column and Sephadex LH-20 column chromatographies and HPLC. Based on various NMR studies including ¹H-¹H COSY. ¹H-^(13)C COSY and HMBC experiments. the active compound was identified as fusidic acid.
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